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Synthesis and biological evaluation of pyrrole-2-carboxamide derivatives: oroidin analogues

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Category
Articles
Authors
Afsar Ali Siddiki
Publisher
Springer International Publishing
Publishing Date
01-Mar-2014
volume
23
Issue
3
Pages
1387-1396
doi
http://doi.org/10.1021/jm00269a01

The reaction of pyrrole or dibromopyrrole-2-trichloroacetone with various amines results in the series of novel pyrrole-2-carboxamide bearing aromatic heterocycle or aryl or alkyl groups. Synthesized molecules were evaluated for their in vitro antibacterial activities. Most of the compounds exhibited potent activity against both Gram-positive and negative pathogens

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AFSAR ALI SIDDIKI. (2014).
Synthesis and biological evaluation of pyrrole-2-carboxamide derivatives: oroidin analogues. Medicinal Chemistry Research,23(3): 1387-1396.doi: http://doi.org/10.1021/jm00269a01
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