The establishment of Somaiya Vidyavihar was the fulfilment of the dream of Late Padmabhushan Pujya Shree Karamshibhai Jethabhai Somaiya – an industrialist of distinction and a great visionary. The foundation stone of K.J.Somaiya College of Arts and Science was laid under the auspices of the somaiya Vidyavihar Trust in 1959. It was the beginning of many educational institutions growing on the vast campus of Somaiya Vidyavihar in future. Presently, thirty four institutions of Somaiya Vidyavihar enrol about 27,000 students and have 1700 faculty members, who impart value based quality education
The College was formerly known as K.J.Somaiya College of Arts and Science.In 1972 it was bifurcated, one of them being, K.J.Somaiya College of Science. The Commerce Faculty was introduced in 1986 and the College was then rechristened as K.J.Somaiya College of Science and Commerce.